RecruitingNCT06363123

Plasma Metabolic Biomarkers for Multi-Cancer Diagnosis

Identification and Validation of Plasma Diagnostic Biomarkers for Multi-Cancer Based on Metabolomics: A Multi-Center Clinical Research and Validation Trial

Sponsor

Beijing Friendship Hospital

Enrollment

2,700 participants

Start Date

Mar 29, 2024

Study Type

OBSERVATIONAL

Conditions

Breast Cancer Liver Cancer Colorectal, Cancer Esophageal Cancer Pancreatic Cancer Gastric Cancer Ovarian Cancer Cervical Cancer Prostate Cancer Cholangiocarcinoma Lung Cancer Renal Cell Carcinoma Thyroid Cancer

Summary

The aim of this observational study is to comprehensively analyze the metabolites in plasma samples from multi-cancer patients using advanced mass spectrometry detection technology, in conjunction with metabolomics approaches. The goal is to construct a plasma metabolite database for multi-cancer patients. Simultaneously, we will delve into the exploration and validation of a series of metabolic biomarkers for early multi-cancer diagnosis. The objective is to establish a safer, more convenient, and more sensitive early screening method, thereby providing a reliable scientific foundation and critical evidence for improving the early diagnostic process for individuals at high risk of multi-cancer.

Eligibility

Plain Language Summary

Simplified for easier understanding

This study investigates whether certain markers in the blood (metabolic biomarkers in plasma) can detect multiple types of cancer early, using a simple blood test. The goal is to develop a non-invasive way to screen for cancer. **You may be eligible if...** - You have a confirmed cancer diagnosis based on established clinical standards, OR - You are a healthy person (no cancer) who is 45 or older and had a normal routine check-up - In either case, your full clinical information must be available **You may NOT be eligible if...** - You already received anti-cancer treatment (chemotherapy, radiation, etc.) before the blood sample was taken - You have more than one type of cancer - Your blood sample was not collected before treatment - You are pregnant - You have a severe acute illness or infection at the time of blood collection Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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