RecruitingNCT06386185

Developing the Probability Algorithm for Pulmonary Hypertension Echocardiography


Sponsor

Royal United Hospitals Bath NHS Foundation Trust

Enrollment

2,500 participants

Start Date

Sep 6, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to assess the efficacy that the addition of novel markers cardiac function, particularly of right ventricular (RV) function in echocardiography, and ECG have in detecting pulmonary hypertension. The main questions it aims to answer are: Can novel markers in ECG and echocardiography suggest the presence of PH? Can existing screening guidelines be improved with the addition of these markers?


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is building a better tool to diagnose pulmonary hypertension — a condition where blood pressure in the lungs is too high — using heart ultrasound scans. Researchers are analyzing existing patient test data to improve how accurately ultrasound can detect this condition. **You may be eligible if...** - You are 18 or older - You have had a heart ultrasound (echocardiogram), an ECG, and a right heart catheterization as part of your regular care **You may NOT be eligible if...** - You are under 18 - You have a known or suspected heart defect present from birth - You have opted out of allowing your health data to be used for research in England or Scotland Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTElectrocardiogram

Non-invasive multi-vector voltage/time graph visualising the electrical conduction of the heart

DIAGNOSTIC_TESTTransthoracic echocardiogram

Non-invasive 2 \& 3 dimensional imaging of the heart using ultrasound

DIAGNOSTIC_TESTRight heart catheter

Minimally invasive cardiac chamber pressure measurement using balloon catheterisation


Locations(5)

Royal United Hospital NHS Foundation Trust

Bath, Banes, United Kingdom

Golden Jubilee Hospital

Glasgow, Lanarkshire, United Kingdom

Sheffield Teaching Hospitals NHS Foundation Trust

Sheffield, South Yorkshire, United Kingdom

Royal Papworth Hospital

Cambridge, United Kingdom

Royal Free NHS Foundation Trust

London, United Kingdom

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NCT06386185


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