RecruitingNCT06386185

Developing the Probability Algorithm for Pulmonary Hypertension Echocardiography


Sponsor

Royal United Hospitals Bath NHS Foundation Trust

Enrollment

2,500 participants

Start Date

Sep 6, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to assess the efficacy that the addition of novel markers cardiac function, particularly of right ventricular (RV) function in echocardiography, and ECG have in detecting pulmonary hypertension. The main questions it aims to answer are: Can novel markers in ECG and echocardiography suggest the presence of PH? Can existing screening guidelines be improved with the addition of these markers?


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Patients 18+ who have undergone TTE, ECG and RHC as part of their clinical care

Exclusion Criteria3

  • Patients \<18 years old
  • Known or suspected congenital heart disease
  • Patient has opted-out of allowing their data to be used for research and planning (via the national data opt-out choice in England, or equivalent data protection scheme in Scotland)

Interventions

DIAGNOSTIC_TESTElectrocardiogram

Non-invasive multi-vector voltage/time graph visualising the electrical conduction of the heart

DIAGNOSTIC_TESTTransthoracic echocardiogram

Non-invasive 2 \& 3 dimensional imaging of the heart using ultrasound

DIAGNOSTIC_TESTRight heart catheter

Minimally invasive cardiac chamber pressure measurement using balloon catheterisation


Locations(5)

Royal United Hospital NHS Foundation Trust

Bath, Banes, United Kingdom

Golden Jubilee Hospital

Glasgow, Lanarkshire, United Kingdom

Sheffield Teaching Hospitals NHS Foundation Trust

Sheffield, South Yorkshire, United Kingdom

Royal Papworth Hospital

Cambridge, United Kingdom

Royal Free NHS Foundation Trust

London, United Kingdom

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NCT06386185


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