Fentanyl Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Spinal Anesthesia ; Peritoneal Symptomatic Effects
Fentanyl Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Spinal Anaesthesia for Appendectomy Patients; Peritoneal Symptomatic Effects: A Randomized Clinical Trial
Aswan University
148 participants
Jul 1, 2023
INTERVENTIONAL
Conditions
Summary
To compare whether 5 μg dexmedetomidine with 25 μg fentanyl added to 0.5% hyperbaric bupivacaine as adjuvants in spinal anaesthesia in patients undergoing appendectomy could reduce intraoperative peritoneal related symptoms.
Eligibility
Inclusion Criteria2
- ASA physical status class I and II.
- Age between 18 - 60 years of either sex.
Exclusion Criteria7
- ASA grade III and IV.
- Infection at the site of injection.
- Coagulopathy or anticoagulation.
- Congenital anomalies of lower spine.
- Active disease of CNS.
- History of allergy to local anesthetics or the adjuvants.
- Complicated appendicitis.
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Interventions
Compare between the efficacy of dexmedetomidine and fentanyl as adjuvants on decreasing the intraoperative peritoneal symptoms such as abdominal discomfort or visceral pain, nausea and vomiting, vagal symptoms like bradycardia and hypotension during appendectomy.
Compare between the efficacy of dexmedetomidine and fentanyl as adjuvants on decreasing the intraoperative peritoneal symptoms such as abdominal discomfort or visceral pain, nausea and vomiting, vagal symptoms like bradycardia and hypotension during appendectomy.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06386783