RecruitingNot ApplicableNCT06426615

Connectivity and Neural Signatures of Consciousness in Unresponsive States

Connectivity and Neural Signatures of Consciousness In Unresponsive States (CONSCIUS) - a Study of Brain Activity in Disorders of Consciousness


Sponsor

Universitaire Ziekenhuizen KU Leuven

Enrollment

20 participants

Start Date

Jan 1, 2024

Study Type

INTERVENTIONAL

Summary

The CONSCIUS study is a prospective, interventional study including patients with acute brain injury and impaired consciousness implanted with intracranial electrodes. The aim of the study is to investigate seizures and thalamocortical neural dynamics underlying behavioral unresponsiveness.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • years old or older
  • Brain injury of any kind, with impaired consciousness or suspected seizures

Exclusion Criteria3

  • < 18 years old
  • Known pregnancy
  • Any condition that, in the judgement of the investigator, makes participation in the study unsafe or unfeasible (e.g., irreversible coagulopathy, large intracranial tumors, surgical technical problems…)

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Interventions

DEVICEIntracranial electrodes

Placement of intracranial electrodes in the cortico-subcortical system


Locations(1)

UZLeuven

Leuven, Vlaams-Brabant, Belgium

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NCT06426615