Acute brain injury Clinical Trials

12 recruitingLast updated: June 17, 2026

There are 12 actively recruiting acute brain injury clinical trials across 9 countries. Studies span Not Applicable, Phase 2, Phase 3. Top locations include Nantes, France, Poitiers, France, Angers, France. Updated daily from ClinicalTrials.gov.


Acute brain injury Trials at a Glance

12 actively recruiting trials for acute brain injury are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Nantes, Poitiers, and Angers. Lead sponsors running acute brain injury studies include Rigshospitalet, Denmark, Erasme University Hospital, and Children's Mercy Hospital Kansas City.

Browse acute brain injury trials by phase

Treatments under study

About Acute brain injury Clinical Trials

Looking for clinical trials for Acute brain injury? There are currently 10 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Acute brain injury trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Acute brain injury clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Phase 2

Feasibility and Safety of Targeting Neutral vs Liberal Fluid Balance in Traumatic Brain Injured Patients- LIMIT-TBI Trial

Acute brain injuryTraumatic Brain InjuryNeurocritical Care+1 more
Erasme University Hospital88 enrolled3 locationsNCT07625995
Recruiting

Physical Mobilisation to Acquired Brain Injury Patients in Intensive Care Units: a Prospective Cohort Study

Acute brain injury
Rigshospitalet, Denmark198 enrolled2 locationsNCT07548580
Recruiting
Phase 3

PRophylaxis Against Early VENTilator-associated Infections in Acute Brain Injury

Intensive Care MedicineAcute brain injuryQuality of Life+4 more
The George Institute3,300 enrolled9 locationsNCT06819592
Recruiting
Not Applicable

Circadian Rhythmicity During Coma Awakening

Acute Brain Injury Coma
Hospices Civils de Lyon90 enrolled1 locationNCT06245434
Recruiting

VentricuLostomy AssoCiaTed InfeCtions (LACTIC): Focus on CSF Lactate and Sampling Site

Acute brain injuryHydrocephalusExternal Ventricular Drain+1 more
Rigshospitalet, Denmark148 enrolled1 locationNCT07380477
Recruiting

IMMUNOREA - Immunological and Inflammatory Determinants Associated With the Prognosis of Intensive Care Patients

Intensive care patientsCritical IllnessCritical Illness Requiring Intensive Care - Sepsis+3 more
Assistance Publique - Hôpitaux de Paris540 enrolled1 locationNCT07345169
Recruiting
Not Applicable

Contribution of Transthoracic and Transcranial Ultrasonography to the Titration of PEEP in Patients With ARDS and ABI

Acute brain injuryAcute Respiratory Distress Syndrome (ARDS)
Theodoros Schizodimos30 enrolled1 locationNCT07248995
Recruiting

Weaning From Mechanical Ventilation in Patients With Acute Brain Injury

Acute brain injuryVentilator Lung
Southeast University, China406 enrolled2 locationsNCT06542107
Recruiting
Not Applicable

Brain-injured Patients Extubation Readiness Study

Acute brain injuryMechanical VentilationMechanical Ventilator Weaning+2 more
University Hospital, Clermont-Ferrand660 enrolled21 locationsNCT04080440
Recruiting
Not Applicable

ECMO ABI Detection With Hyperfine

Acute brain injuryStroke, AcuteExtracorporeal Membrane Oxygenation Complication+1 more
Children's Mercy Hospital Kansas City30 enrolled1 locationNCT06469801
Recruiting
Not Applicable

Connectivity and Neural Signatures of Consciousness in Unresponsive States

Acute brain injuryTraumatic Brain InjurySeizures+1 more
Universitaire Ziekenhuizen KU Leuven20 enrolled1 locationNCT06426615
Recruiting

Non Traumatic Neuro-Vascular Diseases Critical Complications : a Prospective Cohort Study

Non Traumatic Acute Brain Injury
Nantes University Hospital5,000 enrolled6 locationsNCT02714387