Effects of L-arginine and Liposomial Vitamin C on Severe Copd Patients Undergoing Pulmonary Rehabilitation.

This study tests whether taking L-arginine (an amino acid) and liposomal Vitamin C (a highly absorbable form of Vitamin C) can help people with severe COPD (chronic obstructive pulmonary disease — a serious lung condition that makes breathing very difficult) do better during a breathing rehabilitation program. **You may be eligible if...** - You have severe COPD with low blood oxygen levels while breathing normal air - You are between 40 and 90 years old - You are enrolled in a pulmonary rehabilitation program at one of 12 Italian hospitals **You may NOT be eligible if...** - You have taken ergogenic (performance-enhancing) supplements in the last 2 months - You had a severe COPD flare-up in the last 3 months - You have heart disease, heart failure, major heart rhythm problems, or a recent blood clot in the lungs - You have a neuromuscular disease, orthopaedic condition that limits exercise, or significant memory problems Talk to your doctor to see if this trial is right for you.