RecruitingNot ApplicableNCT06446830

The Analgesic Efficacy of Vitamin B Complex in Critically Ill Obstetrics After Caesarean Section

The Analgesic Efficacy of Vitamin B Complex with Paracetamol and Non-steroidal Antiinflammatory Medication in Critically Ill Obstetrics After Caesarian Section; a Prospective Randomized , Placebo-controlled and Double-blinded Study


Sponsor

Ain Shams University

Enrollment

100 participants

Start Date

May 25, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

We aim to investigate the value of vitamin B (B1, B6, B9, B12) on post-cesarean section analgesia in addition to the standard opioid-sparing multimodal regimen to achieve more robust analgesia with minimal side effects.


Eligibility

Sex: FEMALE

Inclusion Criteria1

  • Critically ill -obstetric patients who will be delivered by cesarean section under neuraxial anesthesia.

Exclusion Criteria7

  • Patient's Refusal to participate
  • Known allergy to one or more of the given components.
  • Disturbed conscious level.
  • Prolonged or complicated surgery; defined by operative time of more than 90 min.
  • Severe liver dysfunction or failure
  • Severe renal dysfunction or failure.
  • Severe thrombocytopenia; platelets less than 50

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Interventions

DRUGmultimodal analgesia and vitamin B

B1, B6 , B9 , B12 in addition to the routine paracetamol and NSAID

DRUGstandard multimodal analgesia

Routine Paracetamol and NSAID


Locations(1)

Ain shams university

Cairo, Egypt, Egypt

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NCT06446830


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