RecruitingNot ApplicableNCT06468696

Improvements in Thyroid Tumor Surgery and the Prognosis, Diagnosis, Recurrence and Metastasis of Patients


Sponsor

Second Affiliated Hospital of Xi'an Jiaotong University

Enrollment

170 participants

Start Date

Apr 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of this research is to investigate the clinical outcomes of modified surgical techniques such as omitting the cervical linea alba suture in transthoracic endoscopic thyroidectomy. Furthermore, the study requires the collection of normal thyroid tissues, benign and malignant thyroid tumors, and lymph nodes to further clarify the mechanisms associated with the initiation, progression, metastasis, and recurrence of thyroid cancer.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria5

  • Perform transthoracic endoscopic thyroidectomy via breast approach;
  • Postoperative pathology confirms benign or malignant thyroid tumors;
  • Preoperative thyroid ultrasound or cervical CT suggests no extrathyroidal invasion or distant metastasis of the tumor;
  • No contraindications for general anesthesia;
  • Patients with cosmetic requirements.

Exclusion Criteria5

  • Underwent transthoracic endoscopic thyroidectomy;
  • Postoperative pathology confirmed as benign or malignant thyroid tumors;
  • Preoperative thyroid ultrasound or neck CT suggested no extraglandular invasion or distant metastasis of the tumor;
  • No contraindications to general anesthesia;
  • Patients with cosmetic demands.

Interventions

PROCEDURESuturing the cervical linea alba during endoscopic thyroid surgery.

Suturing the cervical linea alba during endoscopic thyroid surgery.

GENETICPerforming transcriptome sequencing

Performing transcriptome sequencing


Locations(1)

Xi'an Jiaotong University Second Affiliated Hospital

Xi'an, Shaanxi, China

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NCT06468696


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