RecruitingNCT06503640

Coronary Microvascular Dysfunction in Angina Patients With Non-obstructive Coronary Artery Disease (ANOCA-CMD)

Coronary Microvascular Dysfunction in Angina Patients With Non-obstructive Coronary Artery Disease


Sponsor

China-Japan Friendship Hospital

Enrollment

100 participants

Start Date

Jul 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to explore the incidence and effect on prognosis of coronary microvascular dysfunction in patients present of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) \>0.80.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • presence of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) >0.80

Exclusion Criteria5

  • acute myocardial infarction
  • significant valvular heart disease
  • advanced chronic kidney disease
  • patients with significant epicardial coronary artery stenosis (>70% in major vessels by diagnostic coronary angiography) needing percutaneous coronary intervention
  • patients unable to provide written informed consent

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Locations(1)

China-Japan Friendship Hospital

Beijing, Beijing Municipality, China

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NCT06503640


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