RecruitingNCT07093528

A Study Of CS Reducer For Symptomatic Heart Failure With HFpEF And CMD

CMR Substudy of Coronary Sinus Reducer for the Management of Symptomatic Heart Failure With a Preserved Ejection Fraction (HFpEF) Associated With Coronary Microvascular Dysfunction (CMD)


Sponsor

Mayo Clinic

Enrollment

25 participants

Start Date

Oct 16, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

To evaluate the effect of CS reducer implantation in patients with HFPEF and CMD on myocardial ischemia, measured by stress myocardial perfusion using cardiovascular magnetic resonance (CMR)


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at the use of a device called a CS Reducer for people with a type of heart failure where the heart muscle pumps normally but the heart is too stiff (called heart failure with preserved ejection fraction, or HFpEF) combined with a condition where blood supply to the heart muscle is reduced (called coronary microvascular dysfunction, or CMD). This is a sub-study using MRI imaging to better understand how the device affects the heart. **You may be eligible if...** - You are 18 years or older - You are already enrolled in the main CS-Reducer HFpEF clinical study at the same institution **You may NOT be eligible if...** - You have metal implants in your body that are not safe for MRI scans - You are unwilling or unable to give written informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTCardiovascular Magnetic Resonance (CMR)

Patients will consent to undergo a 50-minute non-invasive stress perfusion CMR.


Locations(1)

Mayo Clinic

Rochester, Minnesota, United States

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NCT07093528


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