Low-Dose Ketamine Infusion During Burn Wound Care
A Randomized, Placebo-Controlled, Double-Blind Evaluation of Low-Dose Ketamine Infusion During Burn Wound Care Procedures to Improve Pain Intensity and Reduce Opioid Consumption
University of Tennessee
140 participants
Jul 8, 2024
INTERVENTIONAL
Conditions
Summary
The current standard of care (SOC) (i.e. fentanyl and midazolam) offers limited efficacy for preventing or relieving pain. Ketamine infusions may provide the benefits of analgesia, minimize adverse events, and reduce opioid use. The purpose of this study is to determine if adding a low dose ketamine infusion during wound care will safely provide pain relief for patients with burn injury.
Eligibility
Inclusion Criteria1
- Admitted to burn service with thermal injury
Exclusion Criteria7
- unable/unwilling to consent within 72 hours
- unable to report NRS
- known contraindication to ketamine
- < than 18 years of age
- pregnant
- incarcerated
- TBSA over 50 %
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Interventions
Infusion during wound care
Infusion during wound care
Locations(1)
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NCT06506565