Prediction of Significant Liver Fibrosis
Multimodal Digital Image Fusion Technology Based on Deep Learning to Predict Significant Liver Fibrosis and Its Application in Multi-center Research
Huang Haijun
700 participants
Jul 20, 2024
OBSERVATIONAL
Conditions
Summary
The deep learning method based on convolutional neural network (CNN) was used to extract the relevant features of liver fibrosis classification from the multi-modal information of digital pathological sections, clinical parameters and biomarkers of a large number of existing cases of liver puncture, and the U-Net architecture of CNN was used to segment and extract the features of clinical medical images.
Eligibility
Inclusion Criteria3
- Age of 18-60 years old
- The diagnosis of chronic hepatitis B is in line with the diagnostic criteria of China's 2019 Chronic Hepatitis B Prevention and Treatment Guidelines, and the diagnosis of non-alcoholic fatty liver is in line with the Asian Pacific Hepatology Association guidelines
- Imaging showed no liver cancer
Exclusion Criteria2
- There are contraindications for liver biopsy
- Liver pathology did not meet the criteria
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Interventions
The fibrosis grades were grouped without drug intervention
Locations(1)
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NCT06509230