Single-cell Multiomics and Spatiotemporal Omics Analyze the Mechanism of Liver Degenerative Disease

This research study is using advanced laboratory techniques (single-cell and spatial analysis) to better understand how liver diseases develop and progress — from fatty liver to fibrosis and cirrhosis. Researchers are collecting liver tissue samples from patients having surgery or biopsies for various liver conditions. This is not a treatment trial. **You may be eligible if...** - You have been diagnosed with a liver condition such as a liver hemangioma (a benign blood vessel growth), focal nodular hyperplasia, fatty liver, hepatitis B infection, liver fibrosis, or cirrhosis - You are already scheduled for liver surgery or a liver biopsy for clinical reasons - There are no age or gender restrictions **You may NOT be eligible if...** - You have HIV infection - You have a blood clotting disorder such as hemophilia - You have a serious underlying illness that affects your immune system Talk to your doctor to see if this trial is right for you.