Effects of an Automatic Oxygen Titration System in People With Hypoxemia During Exercise Training
Automatic Oxygen Titration Versus Constant Oxygen Flow Rates During Exercise Training in Hypoxemic People With Chronic Lung Disease - a Randomized, Double-blind, Controlled Cross-over Pilot Study
Schön Klinik Berchtesgadener Land
15 participants
Aug 14, 2023
INTERVENTIONAL
Conditions
Summary
Long-term oxygen therapy is a fundamental treatment modality for patients with chronic hypoxaemic lung disease. Typically, oxygen is administered at a constant flow rate. However, due to fluctuating activity levels, patients' oxygenation status can vary, potentially leading to oxygen desaturation and increased dyspnoea. Emerging evidence suggests that automatic oxygen titration - a method of adjusting oxygen flow in response to current oxygen saturation - may have acute advantages over constant oxygen flow. The primary objective of this study is to investigate the effect of automatic oxygen titration compared to prescribed constant oxygen flow rates on patients' perceived dyspnoea during exercise endurance training.
Eligibility
Inclusion Criteria6
- Chronic lung disease
- Hypoxemia (pO2< 55mmHg) under room air conditions (rest or during exercise) or SpO2<88% during exercise
- established Long-term oxygen therapy or given indication for a Long-term oxygen therapy/ supplemental oxygen therapy for exercise
- Age: 18 to 80 years
- Participation in an inpatient pulmonary rehabilitation program (Schoen Klinik BGL, Germany)
- Written informed consent
Exclusion Criteria1
- \- Acute exacerbation of underlying pulmonary disease requiring cessation of exercise training.
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Interventions
During five exercise training sessions, oxygen therapy is delivered via prescribed constant oxygen flow
During five exercise sessions, oxygen therapy is delivered via an automatically titrated oxygen flow rate to maintain an SpO2 target of 90-94%.
Locations(1)
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NCT06545851