Risk Factors of Extubation Failure in PICU Patients
The Risk Factors of Extubation Failure in Pediatric Intensive Unite Patients at Sohag University Hospitals
Sohag University
100 participants
May 1, 2024
OBSERVATIONAL
Conditions
Summary
Up to 20% of MV patients experience EF \[10\]. EF is defined as the need to reinsert the endotracheal tube to resume MV in patients extubated for less than 48 hours. It has high rates of morbidity and mortality, prolongs the duration of MV and thus causes a longer stay in the PICU and risk of complications such as the need for tracheostomy, the incidence of pneumonia and pulmonary damage, and finally, costs increase as well and death \[10, 11\] .
Eligibility
Inclusion Criteria3
- All patient at PICU < 18 years subjected to MV through an endotracheal tube at least >12 hours.
- Patients eligible for weaning from MV according to the weaning criteria (Evidence for some reversal of the underlying cause following for respiratory failure, Adequate oxygenation" PaO2/FIO2 ratio ≥ 200, FIO2 ≤ 0.40, PaO2 ≥ 60, PaCO2 ≤ 60 and PEEP ≤ 5 cmH2O.", PH ≥ 7.25, Respiratory rate (RR) ≤ 45 bpm, Heart rate (HR) ≤ 140 bpm,(rapid shallow breathing index = tidal volume / RR) RSBI ≤ 8 breaths/min/ml/kg body weight, Hemodynamic stable, no or minimal vasopressor or inotropes"\[1,12\],.
- Appropriate level of consciousness, No continuous sedation infusion nor neuromuscular blocking agents, afebrile, adequate hemoglobin ≥ 7.5 g/dl and/or no evidence of hemorrhage.
Exclusion Criteria4
- Patients less than 30 days.
- Tracheostomized patients.
- Death on mv ≤ 12 hours.
- Unplanned extubation.
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Locations(1)
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NCT06557941