RecruitingNot ApplicableNCT06598670

Transcranial Direct Current Stimulation on Post Stroke Depression

Effects of Transcranial Direct Current Stimulation on Post Stroke Depression


Sponsor

Riphah International University

Enrollment

56 participants

Start Date

Oct 25, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of the research is to address the critical gap that limited number of RCTs are conducted on this topic. To further explore the efficacy of tDCs, large sample sizes, large follow up period and rigorously controlled randomized clinical trials are necessary. An optimum stimulation protocol is also needed on this study. Previous studies lack information regarding effects of this stimulation on depression, cognition, quality of life in relation to different severity levels of stroke.


Eligibility

Min Age: 25 YearsMax Age: 75 Years

Inclusion Criteria1

  • Stroke for more than 6 months Both gender with equal ratio on stroke severity basis Depression diagnosed by Psychiatrist Mild and moderate Depression at PHQ-9 National Institutes of Health Stroke Scale (NIHSS) for severity level; Mild (1-4), Moderate (5-15), Moderate to Severe (16-20), Severe (21-42)

Exclusion Criteria1

  • Any medical condition like cardiac arrhythmias, uncontrolled hypertension. Individual with any pacemaker and metal implant in body. Patient with any other neurological and psychiatric condition.

Interventions

OTHERtDCS

tDCS will be applied to the M1 area for 20 minutes with 5x7 cm electrodes. The intervention will be applied for eight weeks on alternate days

OTHERConventional treatment

Breathing exercises will be performed


Locations(1)

Pakistan Railway General Hospital

Rawalpindi, Punjab Province, Pakistan

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NCT06598670


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