RecruitingNCT07294274

Construction and Clinical Validation Study of a Prediction Model for Depression After Ischemic Stroke


Sponsor

Min Su

Enrollment

488 participants

Start Date

Nov 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Post-stroke depression (PSD) is the most common neuropsychiatric disorder after a stroke, with an incidence rate of 20% to 60%. PSD is not only associated with higher mortality rates, poorer recovery, more obvious cognitive impairments, greater economic burdens, and lower quality of life, but also brings additional medical expenses and care pressure to families. Society also needs to bear higher medical costs. Currently, the early diagnosis of PSD is difficult, which may lead to poor prognosis after stroke. This study aims to utilize machine learning technology to integrate multi-dimensional indicators of patients with ischemic stroke, establish a risk prediction model for PSD, and assist in early, accurate, and individualized assessment of PSD risk in clinical practice.


Eligibility

Plain Language Summary

Simplified for easier understanding

This study is trying to build a model that predicts which stroke patients may develop depression after a stroke. Researchers will collect information about patients who have recently had a stroke to identify risk factors for depression. **You may be eligible if...** - You recently had an ischemic (blocked artery) stroke - You were admitted to the hospital within 7 days of your symptoms starting - You or a family member can sign a consent form **You may NOT be eligible if...** - You have confusion or severe memory/thinking problems - You have a history of depression, schizophrenia, or bipolar disorder - You have serious hearing loss, coordination problems, or severe difficulty speaking that would prevent neurological testing Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTGroup patients based on whether they have been diagnosed with PSD.

Group patients based on whether they have been diagnosed with PSD.


Locations(1)

The First Affiliated Hospital of Chongqing Medical University

Chongqing, China

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NCT07294274


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