RecruitingNot ApplicableNCT06625372

Comparison of Intralipid With SMOF Lipid Following HSCT

Comparison of the Effect of Intralipid Parenteral Nutritional With SMOF Lipid Parenteral Nutritional on Biochemical Markers, Hematologic Markers, and Clinical Outcomes Following Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)


Sponsor

Shahid Beheshti University

Enrollment

50 participants

Start Date

Oct 12, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to have a successful engraftment in after bone transplantation. Acute leukemia patient of both sexes aged 2 to 18 years, who are transplant candidates, participate in this study. Primary hypothesis is Patients receiving SMOF LIPID will have better grafts than patients receiving intralipid. Also, complications after surgery and malnutrition will be less in this group.


Eligibility

Min Age: 2 YearsMax Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study compares two types of intravenous fat supplements — Intralipid and SMOF Lipid — given to children with acute leukemia who are receiving a bone marrow transplant and cannot eat normally. Researchers want to see which fat supplement is better tolerated and supports recovery. **You may be eligible if...** - You are 18 years old or younger - You have been diagnosed with acute leukemia and are scheduled for a bone marrow (stem cell) transplant - You need intravenous nutrition support - You have no allergy to eggs or soy - Your liver function is within acceptable limits **You may NOT be eligible if...** - You have a severe organ failure or significant liver problems - You have an allergy to eggs or soy protein - You or your guardian are unwilling to continue participating Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTSMOF lipid

The SMOF lipid is given to the patient as a fat component of total parenteral nutrition.

DIETARY_SUPPLEMENTINTRALIPIDS

The Intralipid will be given to the patient as fat component of total parenteral nutrition.


Locations(1)

Children's Medical Center, Pediatrics Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran

Tehran, Iran

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NCT06625372


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