RecruitingNot ApplicableNCT06641115

Integrated Treatment for Opioid Use Disorder and PTSD

Integrated Treatment for Co-Occurring Opioid Use Disorder and Posttraumatic Stress Disorder


Sponsor

Medical University of South Carolina

Enrollment

76 participants

Start Date

Mar 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study will test a therapy intervention, HOPE, for individuals with opioid use disorder and posttraumatic stress disorder. Interested individuals will need to be taking medications for opioid use disorder (e.g., suboxone, naltrexone, methadone). Interested participants will complete a 10-12 week therapy, and be asked to complete surveys.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing an integrated treatment approach for people who have both opioid use disorder (OUD) and post-traumatic stress disorder (PTSD), combining medication-assisted treatment with trauma-focused therapy. **You may be eligible if...** - You are between 18 and 70 years old and English-speaking - You have been diagnosed with both opioid use disorder and PTSD - You have some memory of the traumatic event connected to your PTSD - You are already on a stable dose of medication for opioid use disorder (like methadone or buprenorphine) for at least 1 month **You may NOT be eligible if...** - You have unmanaged psychosis, mania, or bipolar disorder - You are considered an immediate suicide risk - You have another substance use disorder where that other substance is your primary concern - You are already receiving evidence-based therapy for substance use or PTSD outside of your medication program - You have a serious medical condition requiring urgent treatment Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALHOPE Therapy

Helping Opioid Use and PTSD with Exposure (HOPE) therapy is an integrated 10-12 week treatment for opioid use disorder and trauma/posttraumatic stress disorder


Locations(1)

Medical University of South Carolina

Charleston, South Carolina, United States

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NCT06641115


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