migraine headache Clinical Trials

10 recruitingLast updated: June 18, 2026

There are 10 actively recruiting migraine headache clinical trials across 7 countries. Studies span Not Applicable, Phase 4. Top locations include Barcelona, Barcelona, Spain, Beijing, Beijing Municipality, China, Beirut, Beirut, Lebanon. Updated daily from ClinicalTrials.gov.


migraine headache Trials at a Glance

10 actively recruiting trials for migraine headache are listed on ClinicalTrialsFinder across 6 cities in 7 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Barcelona, Beijing, and Beirut. Lead sponsors running migraine headache studies include Arizona State University, Benfida, a department of Handi-Move, and Ain Shams University.

Browse migraine headache trials by phase

Treatments under study

About migraine headache Clinical Trials

Looking for clinical trials for migraine headache? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new migraine headache trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about migraine headache clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 110 of 10 trials

Recruiting
Not Applicable

Light Exposure, Migraine Outcomes, and Sleep Quality

migraine headacheSleepPhotophobia
Arizona State University20 enrolled1 locationNCT07476053
Recruiting
Not Applicable

Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD - a Pilot Study

migraine headacheCluster Headaches and Other Trigeminal Autonomic CephalgiasMigraine Headaches+4 more
Karolinska Institutet40 enrolled1 locationNCT07292090
Recruiting
Not Applicable

A Comparison of Biodegradable and Metal Occluders in Patients With PFO and Migraine

migraine headacheMigrainePFO - Patent Foramen Ovale+1 more
Chinese Academy of Medical Sciences, Fuwai Hospital400 enrolled2 locationsNCT06203873
Recruiting
Not Applicable

Vitamin K2 Supplementation in Adult Episodic Migraine

migraine headacheArterial StiffnessVitamin K Deficiency
Sola Aoun Bahous, M.D. Ph.D.160 enrolled1 locationNCT05943457
Recruiting
Phase 4

Acute Migraine Treatment in the ED With Gepants

Migraine Headaches
Icahn School of Medicine at Mount Sinai100 enrolled1 locationNCT06985342
Recruiting
Phase 4

Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine Attack Using VAS Score Among Patients Attending Headache and Neurology Outpatients Clinic of Ainshams University Hospitals

migraine headacheMigraineMigraine Disease+2 more
Ain Shams University120 enrolled1 locationNCT07022496
Recruiting
Not Applicable

Neuro-Complex & Multi Supplements for Migraine Prevention

migraine headacheMigraineMigraine in Adults
Benfida, a department of Handi-Move120 enrolled1 locationNCT07015411
Recruiting

Molecular Phenotyping of Migraine Patients According to Sex and Age Through CGRP Quantification

migraine headacheMigraine with auraMigraine+5 more
Hospital Universitari Vall d'Hebron Research Institute440 enrolled1 locationNCT06674772
Recruiting

Migraine Attack Pain Phase Prediction Study

migraine headacheMigraine with auraMigraine+2 more
Fundación de Investigación Biomédica - Hospital Universitario de La Princesa70 enrolled1 locationNCT06459635
Recruiting

Changes in the Autonomous Nervous System and in the cranio-facial pain threshold after applying visceral manual therapy in patients with chronic migraine and functional gastrointestinal disorders.

Primary chronic migraine headaches
University institute for research in health sciences (IUNICS)40 enrolled1 locationACTRN12621001381875