Real-life Evaluation of the Efficacy of Biologicals in Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
Real-life Evaluation of the Efficacy of Biologicals in CRSwNP
Universitaire Ziekenhuizen KU Leuven
300 participants
Sep 23, 2022
OBSERVATIONAL
Conditions
Summary
The goal of this observational study is to learn more about the real-world efficacy of biologics in patients with chronic rhinosinusitis with nasal polyposis (CRSwNP). All patients who are 18 years or older, who have CRSwNP and are eligible for reimbursement of a biological for the indication of CRSwNP can be included. The main question is the efficacy of biologics in real life after 24 weeks. The main focus are patient reported outcomes measured via several questionnaires and the nasal polyp score, scored with nasal endoscopy.
Eligibility
Inclusion Criteria4
- Participant must be at least 18 years of age at the time of signing the informed consent.
- Capable of giving signed informed consent.
- Participants should have CRSwNP.
- Participants should fulfil the reimbursement criteria for their prescribed biological (omalizumab, mepolizumab and/or dupilumab).
Exclusion Criteria1
- \. Patients treated with other biological therapies in the 3 months prior to the current biological (this is not applicable to patients who are in the trial and switch biological).
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Interventions
biological prescribed as add-on treatment as part of the standard of care
biological prescribed as add-on treatment as part of the standard of care
biological prescribed as add-on treatment as part of the standard of care
Locations(8)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06683261