Chronic Rhinosinusitis (CRS) Clinical Trials

7 recruiting

Chronic Rhinosinusitis (CRS) Trials at a Glance

8 actively recruiting trials for chronic rhinosinusitis (crs) are listed on ClinicalTrialsFinder across 6 cities in 14 countries. The largest study group is Not Applicable with 2 trials, with the heaviest enrollment activity in Leuven, Amsterdam, and Asahikawa. Lead sponsors running chronic rhinosinusitis (crs) studies include Foundation University Islamabad, Indiana University, and Cedars-Sinai Medical Center.

Browse chronic rhinosinusitis (crs) trials by phase

Treatments under study

About Chronic Rhinosinusitis (CRS) Clinical Trials

Looking for clinical trials for Chronic Rhinosinusitis (CRS)? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Chronic Rhinosinusitis (CRS) trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Chronic Rhinosinusitis (CRS) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting

Propel Drug-Eluting Sinus Implant Family IBUKI Cohort

Chronic Rhinosinusitis (CRS)
Medtronic100 enrolled1 locationNCT07546682
Recruiting
Phase 3

Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy

Chronic Rhinosinusitis (CRS)Cystic Fibrosis (CF)
Indiana University64 enrolled1 locationNCT06996951
Recruiting
Not Applicable

Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures

Thyroid NodulesInferior Turbinate HypertrophyChronic Rhinosinusitis (CRS)+2 more
Cedars-Sinai Medical Center184 enrolled1 locationNCT07299474
Recruiting
Phase 1

A Phase I Study Evaluating the Safety, Tolerability, and Pharmacokinetics of VVN432 Nasal Spray

Chronic Rhinosinusitis (CRS)
VivaVision Biotech, Inc60 enrolled1 locationNCT07259538
Recruiting

CRS Questionnaire Validation Project

Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps
The European Forum for Research and Education in Allergy and Airway Diseases1,000 enrolled32 locationsNCT06970977
Recruiting
Phase 1Phase 2

Effectiveness of Penthrox vs Placebo in Sinus Procedures, a Clinical Trial

Chronic Rhinosinusitis (CRS)
St. Paul's Hospital, Canada100 enrolled1 locationNCT06750302
Recruiting
Not Applicable

Comparative Effects of Therapeutic Ultrasound and Sinus Massage in Chronic Rhinosinusitis: a Randomized Controlled Study

Chronic Rhinosinusitis (CRS)
Foundation University Islamabad60 enrolled1 locationNCT06960876
Recruiting

Real-life Evaluation of the Efficacy of Biologicals in Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)

Chronic Rhinosinusitis (CRS)Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Universitaire Ziekenhuizen KU Leuven300 enrolled8 locationsNCT06683261