RecruitingPhase 1NCT06770023

Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension

A Pilot Study of Transseptal ECMO With the Protek Solo Cannula in Lung Transplant Candidates With Right Heart Failure From Pulmonary Hypertension


Sponsor

Mayo Clinic

Enrollment

4 participants

Start Date

Jun 11, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to determine if transseptal extra-corporeal membrane oxygenation (ECMO) can bridge pulmonary hypertension- right heart failure (PH-RVF) patients to lung transplant safely.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is examining a specialized life-support technique called trans-septal ECMO (a machine that takes over heart and lung function) as a temporary bridge to keep critically ill patients with severe pulmonary hypertension (dangerously high blood pressure in the lungs) alive while they wait for a lung transplant. **You may be eligible if...** - You are already listed for a lung transplant - You have been diagnosed with pulmonary hypertension (either primary or secondary to lung disease) - Your right heart is failing despite maximum medication support - You are over 18 years old with a BMI under 35 **You may NOT be eligible if...** - You are in the most critical stage of cardiogenic shock (INTERMACS 1) - You have severe liver or kidney failure - You have evidence of acute brain injury - You have active uncontrolled bleeding or a bleeding disorder - You have a serious active infection Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEProtek Solo Transseptal Cannula

The Protek Solo Transseptal Cannula ECMO cannula will be placed from the right femoral vein and the drainage cannula will be placed from either the left femoral vein or the right internal jugular vein.


Locations(1)

Mayo Clinic in Florida

Jacksonville, Florida, United States

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NCT06770023


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