Vancomycin Reduction Practices (VRP) in the NICU
Implementing Vancomycin Reducing Practices (VRP) in Preterm Infants
Children's Hospital of Philadelphia
13 participants
Jun 2, 2025
INTERVENTIONAL
Conditions
Summary
This multi-center, cluster randomized study aimed at improving implementation of vancomycin reducing practices (VRP) in neonatal intensive care units (NICUs). Sites will be recruited and randomized to receive either external facilitation or no external facilitation to assess the effect on center-level fidelity to the core components of VRP implementation. Interventions available to both study arms are directed at hospital staff and includes identification of local champions, educational outreach, unit-level audit \& feedback, and use of a clinical decision support tool.
Eligibility
Inclusion Criteria3
- Level III NICU
- Affiliated with Kaiser Permanente Northern California (KPNC) or Children's Hospital of Philadelphia Newborn Care Network (CNBCN)
- Recruited by study team
Exclusion Criteria1
- Site not recruited for the study
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Interventions
Designated external facilitators will conduct monthly meetings with local champions at each site. Designated facilitators will follow the developed facilitation guide, that includes content area to cover in each meeting, case scenarios as examples, and tips on how to communicate and support the internal facilitators. The goal is to enable problem-solving and support the local champion in implementing VRP with fidelity
Locations(13)
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NCT06772675