Dexmedetomidine and Dexamethasone Added as Adjuvant Infraclavicular Brachial Plexus Block in Upper Limb Surgery
Comparison of the Anesthetic Effects of Dexmedetomidine and Dexamethasone Added as Adjuvant to Ultrasonography-Guided Infraclavicular Brachial Plexus Block in Upper Limb Surgery
Umraniye Education and Research Hospital
44 participants
Feb 1, 2026
OBSERVATIONAL
Conditions
Summary
The aim of this study was to investigate the effect of dexmedetomidine and dexamethasone added during USG-guided infraclavicular block on block onset time, total block time and time to first analgesic need in patients undergoing upper extremity surgery.
Eligibility
Inclusion Criteria2
- years
- ASA I-II
Exclusion Criteria20
- Under 18 years of age and older than 70 years of age,
- presence of brachial plexus injury,
- patients with bleeding diathesis,
- presence of allergy, -contralateral diaphragmatic paralysis, -
- presence of nerve injury secondary to trauma,
- pre-existing neuropathy of the surgical extremity,
- presence of severe pulmonary,
- renal and hepatic disease,
- congestive heart failure (NYHA stage 3-4),
- uncontrolled diabetes mellitus,
- history of neuromuscular disease,
- patients with extreme obesity or malnutrition (BMI \> 30 kg-1m2 or BMI \<20 kg-1m2),
- presence of epilepsy,
- history of peripheral vascular disease,
- history of chronic pain or fibromyalgia,
- pregnant and lactating patients,
- patients with local infection at the injection site,
- patients undergoing general anesthesia due to inadequacy of the block,
- patients refusing to give informed consent,
- history of recreational substance use, and chronic narcotic-based painkillers
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Interventions
Infraclavicular block with Dexmedetomidine and Dexamethasone was performed at least 30 min before the start of the operation. The patient was positioned in a supine position arms at the sides or in 90 degree abduction, head turned to the other side. Infraclavicular block was performed with the lateral sagittal technique, while the USG probe was placed under the clavicle and medial to the coracoid process, providing a brachial plexus image in the form of a hyperechoic outer ring and hypoechoic circles, like a classic honeycomb image. A local anesthetic mixture was injected with a 100 mm block needle with negative aspiration and its spread in tissue planes was observed. If the VAS score was 3 or above, tramadol 1 mg kg-1 was administered as an analgesic drug.
Locations(1)
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NCT06779604