RecruitingNot ApplicableNCT06788886

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

Enhancing Brain and Mental Health Through Respiratory Training: Clinical Applications in Cancer and Neurodegenerative Disease Care for Patients and Caregivers (Breathing Study)


Sponsor

Mayo Clinic

Enrollment

147 participants

Start Date

Feb 5, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This clinical trial studies the effect of respiratory training for enhancing brain and mental health among patients with multiple sclerosis (MS) and cancer (along with their caregivers). The relationship between respiration, cardiovascular effects in the brain, mental health, and neurophysiological mechanisms are significant for patient populations facing complex health challenges, such as those with cancer and neurodegenerative disease, and their caregivers. By measuring oxygen delivery to brain tissues and cerebrospinal fluid flow, this trial may help researchers investigate the potential benefits of respiratory training for patients with MS and cancer and their caregivers.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether a structured breathing practice can improve brain function and mental health in people with cancer or neurodegenerative diseases (like Parkinson's or Alzheimer's). The study has two parts: one for the general public and one focused on cancer patients and their caregivers. **You may be eligible if...** - You are physically able to do light exercise - You can read and understand English well enough to follow instructions and complete surveys - You have access to a smartphone or tablet - For Study 2: You have prostate cancer, a neuroendocrine tumor, or brain cancer (any stage) — or you are the caregiver of someone with one of these conditions **You may NOT be eligible if...** - You are not physically able to participate in light exercise - You cannot understand English well enough to participate - You do not have access to a smartphone or tablet - Your cancer type (for Study 2) does not match the ones listed above Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBiospecimen Collection

Undergo blood sample collection

OTHERExercise Intervention

Participate in walking routines

PROCEDUREMagnetic Resonance Imaging

Undergo MRI

OTHERQuestionnaire Administration

Ancillary studies

PROCEDURERespiratory Therapy

Participate in breathing sessions


Locations(1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States

View Full Details on ClinicalTrials.gov

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NCT06788886


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