Malignant Brain Neoplasm Clinical Trials

13 recruiting

Malignant Brain Neoplasm Trials at a Glance

14 actively recruiting trials for malignant brain neoplasm are listed on ClinicalTrialsFinder across 6 cities. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Los Angeles, Rochester, and Ann Arbor. Lead sponsors running malignant brain neoplasm studies include Mayo Clinic, Jonsson Comprehensive Cancer Center, and City of Hope Medical Center.

Browse malignant brain neoplasm trials by phase

Treatments under study

About Malignant Brain Neoplasm Clinical Trials

Looking for clinical trials for Malignant Brain Neoplasm? There are currently 13 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Malignant Brain Neoplasm trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Malignant Brain Neoplasm clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 114 of 14 trials

Recruiting
Phase 2

An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors

Malignant Brain Neoplasm
Mayo Clinic47 enrolled1 locationNCT06667726
Recruiting
Not Applicable

Cancer Genetic Testing in Ethnic Populations

Breast CarcinomaHead and Neck CarcinomaMalignant Brain Neoplasm+8 more
Mayo Clinic1,800 enrolled2 locationsNCT04475640
Recruiting
Phase 1

Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and Young Adult Patients With Resectable, Recurrent Primary Malignant Brain Tumors

Resectable Brain NeoplasmRecurrent Diffuse Hemispheric Glioma, H3 G34-MutantRecurrent Malignant Brain Neoplasm
University of Michigan Rogel Cancer Center11 enrolled1 locationNCT06914479
Recruiting
Phase 1

CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children

Malignant Brain NeoplasmRecurrent Malignant Brain NeoplasmRefractory Malignant Brain Neoplasm
City of Hope Medical Center18 enrolled3 locationsNCT04510051
Recruiting
Phase 1Phase 2

Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery

Malignant Brain NeoplasmMalignant Glioma
Stanford University46 enrolled1 locationNCT03510208
Recruiting
Phase 1

Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors

Malignant Brain NeoplasmMetastatic Malignant Neoplasm in the BrainMeningioma+1 more
Jonsson Comprehensive Cancer Center20 enrolled1 locationNCT06650163
Recruiting
Not Applicable

Advanced Magnetic Resonance Imaging for the Identification of Recurrent Brain Tumors and Radiation Necrosis

Malignant Brain NeoplasmMetastatic Malignant Neoplasm in the Brain
Jonsson Comprehensive Cancer Center42 enrolled1 locationNCT07339085
Recruiting
Not Applicable

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

Malignant Brain NeoplasmMalignant Solid NeoplasmProstate Carcinoma+2 more
Mayo Clinic147 enrolled1 locationNCT06788886
Recruiting
Not Applicable

Educational Tools for the Improvement of Early Advance Care Planning in Adolescents and Young Adults With Advanced Solid Tumors and High-Grade Brain Tumors

Malignant Brain NeoplasmAdvanced Malignant Solid NeoplasmRecurrent Advanced Malignant Solid Neoplasm
Mayo Clinic50 enrolled1 locationNCT07174661
Recruiting
Not Applicable

Intravital Microscopy in Human Solid Tumors

Malignant Brain NeoplasmMalignant Solid NeoplasmAnatomic Stage IV Breast Cancer AJCC v8+20 more
Mayo Clinic85 enrolled1 locationNCT03823144
Recruiting

Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors

Malignant Brain NeoplasmMalignant Solid NeoplasmMalignant Testicular Neoplasm+97 more
University of Southern California250 enrolled1 locationNCT07259304
Recruiting
Phase 2

Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy

Malignant Brain Neoplasm
Mayo Clinic100 enrolled1 locationNCT06377696
Recruiting
Phase 1

Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers

Breast CarcinomaUrothelial CarcinomaOvarian Carcinoma+31 more
Jonsson Comprehensive Cancer Center30 enrolled1 locationNCT07118176
Recruiting
Phase 2

Feasibility of FMISO in Brain Tumors

Malignant Brain Neoplasm
OHSU Knight Cancer Institute50 enrolled1 locationNCT03649880