RecruitingNot ApplicableNCT06797219

Light Therapy Device for Neonatal Intraventricular Hemorrhage Grade 3 and 4


Sponsor

Rutgers, The State University of New Jersey

Enrollment

24 participants

Start Date

Feb 25, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The primary purpose of this study is to serve as a pilot study of the EFIL device treatment feasibility of IVH grades 3,4 to guide development of a larger trial. Primary outcomes will assess the following: safety of intervention, recruitment and consent process, acceptability of intervention by parents, retention rates, selection of most appropriate outcome measures, provide sample size estimates for a larger trial, increase the researchers\' experience with the study intervention. A complete list of objectives and aims are listed under "Objectives". This study hopes to treat 12-24 neonates using 650nm light of irradiance 10mW/cm2 for 5 minutes twice a day each day for 12 days. We will also call the parents at 6 months and 12 months to track developmental milestones.


Eligibility

Min Age: 0 DaysMax Age: 1 Month

Plain Language Summary

Simplified for easier understanding

This study tests a light therapy device designed to treat severe brain bleeds in newborns called intraventricular hemorrhage (IVH) — bleeding inside the fluid-filled spaces of the brain. Grade 3 and 4 IVH are the most serious forms and can cause lasting brain damage. The device uses light-based therapy to potentially reduce injury and support healing. **You may be eligible if...** - Your baby is a newborn (under 1 month old) - Your baby has been diagnosed with grade 3 or grade 4 intraventricular hemorrhage (IVH) — a severe bleed in the brain **You may NOT be eligible if...** - Your baby does not have grade 3 or 4 IVH - Your baby is older than 1 month Talk to your doctor to see if this trial is right for your baby.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICELow Level Laser Therapy for Intraventricular Hemorrhage of Prematurity

The experimental arm will be administered treated with the study device. It will be 10 mW/cm\^2 of 650nm laser through use of a novel laser device given for 5 minutes twice daily for 12 days.


Locations(2)

Rutgers - New Jersey Medical School / University Hospital

Newark, New Jersey, United States

Newark Beth Israel Medical Center

Newark, New Jersey, United States

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NCT06797219


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