Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation

This study is examining how the heart remodels and recovers after surgery to fix a leaky aortic valve (aortic regurgitation), specifically in patients who also have a mildly leaky mitral valve and a very enlarged left ventricle. **You may be eligible if...** - You are 18 or older - You are scheduled for elective (non-emergency) surgery to repair or replace a chronically leaky aortic valve - You also have a mildly leaky mitral valve caused by the heart's enlargement (functional mitral regurgitation) - Your left ventricle (main pumping chamber) is significantly enlarged (end-diastolic volume at least 250 mL) **You may NOT be eligible if...** - You have an active heart infection (endocarditis) - You have had a previous heart attack - You need bypass surgery at the same time - Your aortic valve problem came on suddenly (acute) - You have a pre-existing cause of an enlarged left ventricle unrelated to the leaky aortic valve - You have long-term persistent or permanent atrial fibrillation - You are pregnant or plan to become pregnant within 12 months of surgery - You have a pacemaker Talk to your doctor to see if this trial is right for you.