Mitral Valve Regurgitation Clinical Trials

9 recruiting

Mitral Valve Regurgitation Trials at a Glance

11 actively recruiting trials for mitral valve regurgitation are listed on ClinicalTrialsFinder across 6 cities in 14 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Cleveland, New York, and Atlanta. Lead sponsors running mitral valve regurgitation studies include American College of Cardiology, Annetine Gelijns, and 4C Medical Technologies, Inc..

Browse mitral valve regurgitation trials by phase

Treatments under study

About Mitral Valve Regurgitation Clinical Trials

Looking for clinical trials for Mitral Valve Regurgitation? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Mitral Valve Regurgitation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Mitral Valve Regurgitation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting
Not Applicable

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Mitral Valve Regurgitation
Medtronic Cardiovascular1,056 enrolled85 locationsNCT03242642
Recruiting
Not Applicable

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

Mitral Valve Regurgitation
Annetine Gelijns450 enrolled61 locationsNCT05051033
Recruiting
Not Applicable

TVMR With the INNOVALVE System Trial - Early Feasibility Study

Mitral Valve Regurgitation (Degenerative or Functional)
Edwards Lifesciences65 enrolled17 locationsNCT04919980
Recruiting
Not Applicable

Mitral Annular Repair With the CathHELIX™ Transcatheter System in Subjects With FMR

Mitral Valve Regurgitation (Degenerative or Functional)
HVR Cardio Oy5 enrolled2 locationsNCT07188233
Recruiting

Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation

Diastolic Heart FailureAortic Valve RegurgitationMitral Valve Regurgitation+3 more
Petrovsky National Research Centre of Surgery120 enrolled2 locationsNCT06805253
Recruiting
Not Applicable

AltaValve Pivotal Trial

Mitral RegurgitationMitral Valve RegurgitationMitral Insufficiency+2 more
4C Medical Technologies, Inc.450 enrolled29 locationsNCT06465745
Recruiting
Not Applicable

Mi-thos® Transcatheter Mitral Valve Replacement Study

Mitral Valve Regurgitation
Shanghai NewMed Medical Co., Ltd.122 enrolled3 locationsNCT04195984
Recruiting

STS/ACC TVT Registry Mitral Module

Mitral Valve Regurgitation
American College of Cardiology4,000 enrolled1 locationNCT02245763
Recruiting

GISE Registry of Transcatheter Treatment of Mitral Valve Regurgitation With the MitraClip G4

Mitral Valve Regurgitation
Fondazione GISE Onlus264 enrolled1 locationNCT05455489
Recruiting
Not Applicable

First-In-Human Clinical Study for Treatment of Severe Mitral Valve INsufficiency With Epygon™ TRanscatheter Mitral VAlve System

Mitral Valve Regurgitation
Epygon40 enrolled10 locationsNCT04775108
Recruiting

The Prospecive OBSERVational Munich Interventional MITRAl-Valve Registry

Tricuspid Valve RegurgitationMitral Valve RegurgitationMitral Valve Stenosis
Deutsches Herzzentrum Muenchen5,000 enrolled1 locationNCT04577248