Aortic Valve Regurgitation Clinical Trials

9 recruiting

Aortic Valve Regurgitation Trials at a Glance

10 actively recruiting trials for aortic valve regurgitation are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in San Francisco, Hangzhou, and Cincinnati. Lead sponsors running aortic valve regurgitation studies include Second Affiliated Hospital, School of Medicine, Zhejiang University, JC Medical, Inc., an affiliate of Edwards Lifesciences LLC, and Institut universitaire de cardiologie et de pneumologie de Québec, University Laval.

Browse aortic valve regurgitation trials by phase

Treatments under study

About Aortic Valve Regurgitation Clinical Trials

Looking for clinical trials for Aortic Valve Regurgitation? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Aortic Valve Regurgitation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Aortic Valve Regurgitation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 110 of 10 trials

Recruiting
Not Applicable

J-Valve Transfemoral Pivotal Study

Aortic Valve RegurgitationAortic Valve Disease Mixed
JC Medical, Inc., an affiliate of Edwards Lifesciences LLC194 enrolled37 locationsNCT06455787
Recruiting
Not Applicable

Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR

Aortic Valve StenosisAortic Valve RegurgitationProsthesis Failure
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval310 enrolled7 locationsNCT05459233
Recruiting
Not Applicable

Early Aortic vaLve surgEry Versus wAtchful waitiNg Strategy in Severe Asymptomatic aOrtic reguRgitation

Aortic Valve Regurgitation
Na Homolce Hospital217 enrolled8 locationsNCT05438862
Recruiting

Cohort Observing Mechanisms, Progression and Sequelae of Valvular Heart Disease

Aortic Valve DiseaseHeart Valve DiseaseTricuspid Valve Regurgitation+11 more
Second Affiliated Hospital, School of Medicine, Zhejiang University10,000 enrolled15 locationsNCT07267117
Recruiting

Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation

Diastolic Heart FailureAortic Valve RegurgitationMitral Valve Regurgitation+3 more
Petrovsky National Research Centre of Surgery120 enrolled2 locationsNCT06805253
Recruiting
Not Applicable

Clinical Evaluation of the Free Margin Cusp Sizer (CALIBRATE)

Aortic Valve RegurgitationAortic Root Aneurysm
Cliniques universitaires Saint-Luc- Université Catholique de Louvain120 enrolled1 locationNCT04797572
Recruiting

CT Scan Sizing for Perceval Sutureless Valve

Aortic Valve Regurgitation
Maria Cecilia Hospital50 enrolled1 locationNCT05799573
Recruiting

A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease

Hypertrophic CardiomyopathyCoronary Artery DiseaseCongenital Heart Disease+7 more
McGill University Health Centre/Research Institute of the McGill University Health Centre2,130 enrolled1 locationNCT04464655
Recruiting

Prospective Observational Cohort Study of Moderate Aortic Valve Disease

Aortic Valve DiseaseModerate Aortic Valve StenosisModerate Aortic Valve Regurgitation
Second Affiliated Hospital, School of Medicine, Zhejiang University1,000 enrolled1 locationNCT06595992
Recruiting

Transcatheter Aortic Valve Replacement for Pure Severe Aortic Valve Regurgitation

Aortic Valve Regurgitation
Xijing Hospital500 enrolled1 locationNCT06381271