RecruitingNot ApplicableNCT07088302
Effect OF Lactase Enzyme Supplements ON Intolerance IN Preterm Neonates
Effect OF Lactase Enzyme Supplements ON Protection Against Feeding Intolerance IN Preterm Neonates
Sponsor
Alexandria University
Enrollment
120 participants
Start Date
Aug 30, 2025
Study Type
INTERVENTIONAL
Conditions
Summary
This study aims to study the effect of lactase enzyme in preventing feeding intolerance in preterm neonates in neonatal intensive care unit at Alexandria University Children's Hospital.
Eligibility
Min Age: 3 DaysMax Age: 1 Month
Inclusion Criteria1
- Preterm neonates ≤ 32 weeks gestational age.
Exclusion Criteria7
- Patients with any of the following will be excluded:
- Parental consent lacking/refusal.
- Obvious major congenital abnormalities.
- Infants more than 72 hours of age at the time of randomization.
- Delayed introduction of feeding (beyond three days of life).
- Known galactosemia.
- Severe IUGR. -
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Interventions
DRUGlactase administration
1 drop for each 10 ml of formula milk for 14 days
OTHERplacebo
10 ml milk without lactase
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07088302
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