RecruitingNot ApplicableNCT06821568

Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome

Long-term Home-based Transcranial Electrical Stimulation for Cognitive and Motor Function in Older Adults With an Increased Risk of Dementia: a Randomized Controlled Trial


Sponsor

Hebrew SeniorLife

Enrollment

128 participants

Start Date

Sep 2, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function, dual task standing and walking, and other metrics of mobility in older adults with motoric cognitive risk syndrome (MCR).


Eligibility

Min Age: 65 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether home-based brain stimulation (a non-invasive device worn on the head) can improve walking and thinking in older adults who have Motoric Cognitive Risk Syndrome — a condition combining slow walking and memory complaints that may precede dementia. **You may be eligible if...** - You are between 65 and 90 years old - You have memory complaints (e.g., you feel your memory is worse than others your age) - You have a slow walking speed (below average for your age and sex) - Your cognitive score is 21 or above on the MoCA test (meaning no significant dementia) - You can walk unassisted for at least 2 minutes and manage daily activities independently **You may NOT be eligible if...** - You have a diagnosis of dementia or Parkinson's disease - You have a pacemaker or metal implant in or near your head - You have had a recent stroke or epilepsy - You are currently enrolled in another cognitive intervention trial Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERPersonalized Transcranial Direct Current Stimulation (tDCS)

Home-based transcranial direct current stimulation (tDCS) tailored to target the left dlPFC.

OTHERActive-Sham

Stimulation administered in very low-level currents (0.5 mA total) designed to not significantly influence cortical tissue, but still mimic the cutaneous sensations induced by tDCS.


Locations(2)

Hebrew Rehabilitation Center

Roslindale, Massachusetts, United States

Tel Aviv Sourasky Medical Center

Tel Aviv, Israel

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NCT06821568


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