Towards Cure Via Only Ultra-short ICB in CSCC

This study is testing whether a very short course of immunotherapy (checkpoint inhibitor treatment) can cure people with cutaneous squamous cell carcinoma (CSCC), a type of skin cancer. The goal is to see if fewer doses can still achieve lasting remission. **You may be eligible if...** - You are 18 or older - You have been diagnosed with cutaneous squamous cell carcinoma (a common skin cancer) - Your cancer is at a stage where surgery or standard treatment is planned - You are in good enough health to receive immunotherapy **You may NOT be eligible if...** - You have active autoimmune disease (like lupus or rheumatoid arthritis) - You are on long-term immune-suppressing medications (like steroids) - You have had an organ transplant - You have another active cancer - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.