A Clinical Study of SHR-A1811 Combined With Chemotherapy for Platinum Sensitive Recurrent Ovarian Cancer
An Open, Multicenter Phase Ib / II Clinical Study of SHR-A1811 Combined With Chemotherapy for Platinum Sensitive Recurrent Ovarian Cancer
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
150 participants
Mar 18, 2025
INTERVENTIONAL
Conditions
Summary
The objective is to evaluate the tolerance, safety, pharmacokinetic characteristics and immunogenicity of SHR-A1811 combined with carboplatin and bevacizumab in the treatment of platinum sensitive recurrent epithelial ovarian cancer, and to determine the RP2D of the combination, and preliminarily to evaluate the effectiveness of SHR-A1811 combined regimen in the treatment of platinum sensitive recurrent epithelial ovarian cancer.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
SHR-A1811.
Carboplatin.
Bevacizumab.
Oxaliplatin for injection.
Paclitaxel injection.
Doxorubicin hydrochloride liposome injetction.
Adebrelimab injection.
Locations(1)
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NCT06840002