RecruitingNot ApplicableNCT06883266

Transcranial Direct Current Stimulation for Motor Function and Fatigue in PD

Transcranial Direct Current Stimulation (tDCS) to Improve Motor Function and Motor Fatigue in Parkinson's Patients


Sponsor

Sanford Health

Enrollment

64 participants

Start Date

Nov 11, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The investigators hypothesize that multi-session anodal tDCS (atDCS) of the left primary motor cortex (M1) will induce long-lasting effects in improving motor function and reducing motor fatigue and fatigability in PD patients.


Eligibility

Inclusion Criteria2

  • Clinical diagnosis of PD with at least two of the four diagnostic criteria for PD (tremor, rigidity, bradykinesia, and postural instability)
  • Must be able to consent

Exclusion Criteria7

  • Patients with dementia (MOCA \< 21)
  • PD treatment using deep brain stimulation (DBS)
  • Diagnosis of psychosis
  • Diagnosis of multiple sclerosis
  • Diagnosis of stroke
  • Diagnosis of chronic obstructive pulmonary disease (COPD)
  • Diagnosis of congestive heart failure (CHF)

Interventions

DEVICEtranscranial direct current stimulation (tDCS)

2 mA will be administered for 5 consecutive days for a duration of 20 minutes with electrode placement at the left dorsolateral prefrontal cortex.

DEVICESham (No Treatment)

For 30 seconds, the patient will experience a ramp up of the stimulation, after which point no stimulation will be transmitted for the remainder of the session. This will be administered for 5 consecutive days for a duration of 20 minutes with electrode placement at the left dorsolateral prefrontal cortex


Locations(1)

Sanford Brain and Spine Center

Fargo, North Dakota, United States

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NCT06883266


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