RecruitingNCT06899360

Evaluation of Clinical Progression, Prognostic Factors, and Quality of Life in Patients with Age-related Macular Degeneration.

Evaluation of Clinical Progression, Prognostic Factors, and Quality of Life in Patients with Age-related Macular Degeneration (VERA-nAMD).


Sponsor

University of Udine

Enrollment

200 participants

Start Date

Oct 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The VERA-AMD study is a prospective, observational study designed to evaluate clinical progression, prognostic factors, and quality of life in patients with age-related macular degeneration (AMD). The study aims to analyze real-world clinical data to identify key predictors of disease progression and functional outcomes, with the goal of optimizing AMD management. The study involves 200 patients aged ≥50 with a confirmed diagnosis of AMD, monitored through routine clinical practice. Primary outcomes include progression rates to advanced AMD and changes in visual acuity, while secondary outcomes focus on retinal morphology and quality of life. Anti-VEGF therapy and AI-based fluid analysis will be integrated to explore their impact on disease progression and patient outcomes.


Eligibility

Min Age: 50 YearsMax Age: 120 Years

Inclusion Criteria3

  • age ≥ 50 years.
  • confirmed diagnosis of AMD in at least one eye.
  • follow-up scheduled according to standard clinical practice.

Exclusion Criteria2

  • presence of other significant ocular conditions that could affect visual acuity.
  • systemic conditions that make the patient unsuitable for long-term follow-up.

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Locations(1)

Department of Ophthalmology

Udine, UD, Italy

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NCT06899360


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