RecruitingNCT06958016

Role of Tryptase Levels in Patients With Stable Coronary Artery Disease.

Investigation of the Role and Prognostic Value of Tryptase in Patients With Stable Coronary Artery Disease


Sponsor

University of Thessaly

Enrollment

200 participants

Start Date

Jan 12, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of this study is to measure the levels of serum tryptase and correlate them with the severity of coronary artery disease in study population. In addition, it will evaluate the usability of tryptase levels as a prognostic biomarker for future cardiovascular events.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria3

  • Male and female subjects aged 18 - 85 years old.
  • Clinical symptoms of angina which are classified based on the Canadian Cardiovascular Score (CCS score)
  • Positive SPECT scan for myocardial ischemia

Exclusion Criteria11

  • Acute Coronary Syndrome 4 weeks before the coronary catheterization
  • Percutaneous Coronary Angioplasty
  • Coronary Artery Bypass Graft
  • Active symptoms of allergy (asthma, urticaria)
  • Mastocytosis
  • Hypereosinophilia
  • Autoimmune disease
  • Cancer
  • Kidney failure
  • Myelodysplastic Syndrome
  • Denial of signing informed consent

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Locations(2)

417 Military Hospital NIMTS

Athens, Attica, Greece

Larisa University Hospital

Larissa, Thessaly, Greece

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NCT06958016


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