Chronic Coronary Syndrome Clinical Trials

31 recruitingLast updated: June 18, 2026

There are 31 actively recruiting chronic coronary syndrome clinical trials across 14 countries. Studies span Not Applicable, Phase 4, Phase 3. Top locations include Warsaw, Poland, Gwangmyeong, South Korea, Chongqing, Chongqing Municipality, China. Updated daily from ClinicalTrials.gov.


Chronic Coronary Syndrome Trials at a Glance

31 actively recruiting trials for chronic coronary syndrome are listed on ClinicalTrialsFinder across 6 cities in 14 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in Warsaw, Gwangmyeong, and Chongqing. Lead sponsors running chronic coronary syndrome studies include Medical University of Warsaw, Azienda Ospedaliera "Sant'Andrea", and Samsung Medical Center.

Browse chronic coronary syndrome trials by phase

Treatments under study

About Chronic Coronary Syndrome Clinical Trials

Looking for clinical trials for Chronic Coronary Syndrome? There are currently 31 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Chronic Coronary Syndrome trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Chronic Coronary Syndrome clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 31 trials

Recruiting

Microplastics and Nanoplastics in Patients With Chronic Coronary Syndromes

Pollution; ExposureMicroplasticsNanoplastics+4 more
Azienda Ospedaliera "Sant'Andrea"120 enrolled6 locationsNCT07291609
Recruiting
Phase 3

Comparing High and lOw-dose asPirin With Dual anTIplatelet Therapy for Three Months Using prasUgrel and aSpirin Following Coronary Artery Bypass Grafting. (OPTIMUS-CABG Trial)

Chronic Coronary SyndromeStable Coronary Artery Disease CAD
Dolnośląskie Centrum Chorób Serca im.prof. Zbigniewa Religi MEDINET Sp. z o.o.1,703 enrolled18 locationsNCT07195149
Recruiting

Advanced Invasive Diagnosis Strategy for Post-PCI Patients With Stable Coronary Syndromes Undergoing Coronary Angiography

Chronic Coronary SyndromeAngina, StablePercutaneous Coronary Intervention (PCI)+1 more
Fundacion Investigacion Interhospitalaria Cardiovascular246 enrolled5 locationsNCT07638137
Recruiting

Derivation and Validation of the Aortic Valve Echocardiographic Calcium Score to Confirm Severe Aortic Stenosis: the Echo-AVCS Study

Calcific Aortic StenosisChronic Coronary SyndromeAortic Stenosis+1 more
Azienda Ospedaliera "Sant'Andrea"250 enrolled5 locationsNCT07620925
Recruiting
Not Applicable

Orbital Atherectomy vs Intravascular Lithotripsy for the Treatment of Calcified Coronary Nodules (ORBIT-SHOCK).

Chronic Coronary SyndromeCoronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)+6 more
Spanish Society of Cardiology50 enrolled6 locationsNCT06736665
Recruiting
Phase 4

Effect of ZaStaprazan on Platelet Reactivity of Clopidogrel After PercuTaneous CoronAry InteRvention

Chronic Coronary Syndrome
Yonsei University100 enrolled1 locationNCT07471867
Recruiting
Not Applicable

Artificial Intelligence-Driven Medipixel Fractional Flow Reserve Versus Invasive Fractional Flow Reserve-Guided PCI Trial (AIM-FFR Trial)

Acute Coronary SyndromeCoronary Artery DiseaseChronic Coronary Syndrome
Samsung Medical Center2,100 enrolled23 locationsNCT07329699
Recruiting

Computational mOdelliNg of myoCardial pERfusion to Improve ouTcome Prediction Based on cOronary Artery Stenosis and Atherosclerotic Plaque Burden Assessment by Computed Tomography

Chronic Coronary Syndrome
Centro Cardiologico Monzino400 enrolled1 locationNCT06337461
Recruiting
Not Applicable

Effect of Intensive Lipid-Lowering Therapy on Coronary Atherosclerotic Plaque Progression in Young and Middle-Aged Patients With Chronic Coronary Syndrome

Chronic Coronary Syndrome
Liu yong766 enrolled7 locationsNCT06896708
Recruiting
Not Applicable

Perfusion Estimation For Optimal Treatment Strategy in Chronic Coronary Syndrome

Myocardial IschemiaCoronary Artery DiseaseChronic Coronary Syndrome+1 more
Gødstrup Hospital570 enrolled1 locationNCT05865600
Recruiting
Not Applicable

Drug-Coated Balloon Versus Drug-Eluting Stent for Treatment of De-Novo Coronary Lesions in Patients With High Bleeding Risk-2

Chronic Coronary Syndrome
Samsung Medical Center1,200 enrolled18 locationsNCT06742931
Recruiting
Not Applicable

SECURE Trial: Stress Echocardiography With Carotid Ultrasound vs Routine CT Coronary Angiography in Chronic Coronary Syndrome for Endpoints

Coronary DiseaseCoronary Artery DiseaseChronic Coronary Syndrome
London North West Healthcare NHS Trust2,000 enrolled1 locationNCT06185530
Recruiting

A Study on the Peripheral Blood in Patients With Acute Coronary Syndrome

Acute Coronary SyndromeChronic Coronary Syndrome
Second Affiliated Hospital of Wenzhou Medical University310 enrolled1 locationNCT06955143
Recruiting
Phase 4

Hyperemic mYocardial Perfusion by adEnosine at diffeRent Doses

Coronary Artery DiseaseChronic Coronary SyndromeIschemic Heart Disease
Region Skane180 enrolled1 locationNCT06578234
Recruiting

FAPI Imaging Predicts Adverse Cardiac Events in Chronic Total Occlusion

Chronic Coronary Syndromechronic total occlusion (CTO)
Lin Zhao470 enrolled1 locationNCT07020858
Recruiting

Association of Plasma N-terminal Pro-Brain Natriuretic Peptide Levels With the Burden of Coronary Artery Disease

Chronic Coronary SyndromeCoronary Arterial Disease (CAD)NT-pro-BNP+2 more
IRCCS Ospedale San Raffaele800 enrolled2 locationsNCT07013344
Recruiting

Role of Tryptase Levels in Patients With Stable Coronary Artery Disease.

Chronic Coronary Syndrome
University of Thessaly200 enrolled2 locationsNCT06958016
Recruiting
Not Applicable

CTFFR and Prediction of Non-Significant CAD Lesions

Chronic Coronary Syndrome
Shiraz University of Medical Sciences250 enrolled1 locationNCT06979427
Recruiting
Phase 3

SGLT2 Inhibitor TrEatment iN Patients Awaiting cOronary arTery bYpass Surgery to Reduce Post-opErative AF

Atrial FibrillationChronic Coronary Syndrome
Region Örebro County800 enrolled8 locationsNCT05852704
Recruiting
Not Applicable

Effects of a Healthy Nordic Diet on Atherosclerosis in Patients with Coronary Heart Disease

Coronary DiseaseMASLDMyocardial Infarction+3 more
Uppsala University150 enrolled1 locationNCT06701968