NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of NBI-1117568 in Adults With Schizophrenia Who Warrant Inpatient Hospitalization
The primary objective for this study is to evaluate the efficacy of NBI-1117568 compared with placebo on improving behavioral and psychological symptoms of schizophrenia in adults.
Eligibility
Min Age: 18 YearsMax Age: 65 Years
Plain Language Summary
Simplified for easier understanding
This study is testing a new medication called NBI-1117568 for people with schizophrenia who are experiencing an acute episode (a relapse or worsening of symptoms) serious enough to require hospitalization. The goal is to assess whether this drug is effective and safe for treating active schizophrenia symptoms in an inpatient setting.
**You may be eligible if...**
- You have been diagnosed with schizophrenia
- You are currently experiencing a relapse or worsening of symptoms and need to be hospitalized
- You are willing and able to remain in an inpatient setting for the duration of the study
- You are willing to stop other antipsychotic medications before participating
**You may NOT be eligible if...**
- You have a known allergy to any ingredient in NBI-1117568
- You have an unstable or poorly controlled medical condition or serious chronic illness
- You are considered to be at risk of harming yourself or others
- You have had moderate to severe substance use disorder (other than nicotine or caffeine) within the past 6 months
- You tested positive for alcohol or other prohibited drugs at screening
- You have a history of not following research protocols
Talk to your doctor to see if this trial is right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
DRUGNBI-1117568
NBI-1117568 will be administered per schedule specified in the arm description.
DRUGPlacebo
Placebo will be administered per schedule specified in the arm description.
Locations(21)
Neurocrine Clinical Site
Bryant, Arkansas, United States
Neurocrine Clinical Site
Little Rock, Arkansas, United States
Neurocrine Clinical Site
Anaheim, California, United States
Neurocrine Clinical Site
Pico Rivera, California, United States
Neurocrine Clinical Site
San Diego, California, United States
Neurocrine Clinical Site
Sherman Oaks, California, United States
Neurocrine Clinical Site
Torrance, California, United States
Neurocrine Clinical Site
Hollywood, Florida, United States
Neurocrine Clinical Site
Miami Lakes, Florida, United States
Neurocrine Clinical Site
Atlanta, Georgia, United States
Neurocrine Clinical Site
Decatur, Georgia, United States
Neurocrine Clinical Site
Snellville, Georgia, United States
Neurocrine Clinical Site
Chicago, Illinois, United States
Neurocrine Clinical Site
Gaithersburg, Maryland, United States
Neurocrine Clinical Site
Watertown, Massachusetts, United States
Neurocrine Clinical Site
Marlton, New Jersey, United States
Neurocrine Clinical Site
Staten Island, New York, United States
Neurocrine Clinical Site
The Bronx, New York, United States
Neurocrine Clinical Site
Austin, Texas, United States
Neurocrine Clinical Site
DeSoto, Texas, United States
Neurocrine Clinical Site
Houston, Texas, United States
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.