RecruitingNot ApplicableNCT06979427

CTFFR and Prediction of Non-Significant CAD Lesions

Evaluation of the Ability of CTFFR to Determine Non-significant Lesions of Coronary Disease Based on MACE in One-year Follow-up of Patients (Seeing Beyond the Stenosis: CTFFR and MACE in a One-Year Follow-Up)


Sponsor

Shiraz University of Medical Sciences

Enrollment

250 participants

Start Date

Jan 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

In this prospective cohort study, 250 patients with suspected or known CAD and at least one intermediate coronary lesion (50-70% stenosis) who had a NiFFR value greater than 0.80 underwent coronary computed tomography angiography (CCTA) with NiFFR assessment. Patients were followed for one year to monitor for MACE


Eligibility

Min Age: 20 YearsMax Age: 80 Years

Inclusion Criteria1

  • Patients were enrolled if they had at least one intermediate coronary lesion (classified as 50-70% diameter stenosis on visual judgment) on CCTA and then underwent FFR testing

Exclusion Criteria5

  • Patients having past coronary artery bypass graft surgery (CABG)
  • previous PCI in the target vascular
  • significant renal impairment define with eGFR < 30 mL/min/1.73 m²
  • contrast allergy
  • poor image quality that prevented appropriate CCTA or CT-FFR analysis

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Interventions

DIAGNOSTIC_TESTNIFFR

Fractional flow reserve derived from CT angiography from lesion between 50-70%


Locations(1)

Professor Kojuri Cardiology Clinic

Shiraz, Fars, Iran

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NCT06979427


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