Nicotinamide Mononucleotide in Patients Undergoing Cardiac Surgery
Randomized Clinical Trial of Beta Nicotinamide Mononucleotide in Patients Undergoing Cardiac Surgery
Brigham and Women's Hospital
90 participants
Jun 10, 2026
INTERVENTIONAL
Conditions
Summary
The investigators will perform a phase 2a, randomized, double-blind, placebo-controlled clinical trial in adult patients undergoing elective cardiac surgery to investigate the effects of oral nicotinamide mononucleotide (NMN) administration on myocardial NAD+ concentrations and on postoperative markers of myocardial and kidney injury.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
An orally-administered stable crystalline tablet formulation of NMN
matching placebo tablets
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07013591