RecruitingNCT07099963

Frequency and Severity of Respiratory Acidosis During One-lung Ventilation, a Retrospective Pilot Study to Compare Clinician Settings and Those Proposed by the VentilO Application


Sponsor

Laval University

Enrollment

100 participants

Start Date

Aug 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

One-lung ventilation is a mechanical ventilation method frequently used during several thoracic surgeries. One-lung ventilation requires the use of protective ventilation to limit ventilator-induced injury and reduce postoperative respiratory complications. Protective ventilation during one-lung ventilation is specific since tidal volumes are applied by definition to one lung, and it is recommended to use lower tidal volumes, down to 4 ml/kg of ideal body weight. This approach requires individualized ventilation parameters, which differs from the conventional or two-lung ventilation, and there are no clear recommendations regarding respiratory rate adjustment to ensure adequate gas exchange.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Adults (≥ 18 years old)
  • Patients intubated and undergoing one-lung ventilation during thoracic surgery
  • Volume-controlled ventilation mode used intraoperatively

Exclusion Criteria2

  • Arterial blood gas data unavailable during one-lung ventilation
  • Missing demographic data (sex, height, actual weight)

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Interventions

OTHERone lung ventilation

Arterial blood gases during one lung ventilation


Locations(1)

Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval

Québec, Quebec, Canada

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NCT07099963


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