Frequency and Severity of Respiratory Acidosis During One-lung Ventilation, a Retrospective Pilot Study to Compare Clinician Settings and Those Proposed by the VentilO Application
Laval University
100 participants
Aug 1, 2025
OBSERVATIONAL
Conditions
Summary
One-lung ventilation is a mechanical ventilation method frequently used during several thoracic surgeries. One-lung ventilation requires the use of protective ventilation to limit ventilator-induced injury and reduce postoperative respiratory complications. Protective ventilation during one-lung ventilation is specific since tidal volumes are applied by definition to one lung, and it is recommended to use lower tidal volumes, down to 4 ml/kg of ideal body weight. This approach requires individualized ventilation parameters, which differs from the conventional or two-lung ventilation, and there are no clear recommendations regarding respiratory rate adjustment to ensure adequate gas exchange.
Eligibility
Inclusion Criteria3
- Adults (≥ 18 years old)
- Patients intubated and undergoing one-lung ventilation during thoracic surgery
- Volume-controlled ventilation mode used intraoperatively
Exclusion Criteria2
- Arterial blood gas data unavailable during one-lung ventilation
- Missing demographic data (sex, height, actual weight)
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Interventions
Arterial blood gases during one lung ventilation
Locations(1)
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NCT07099963