Thoracic Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about Thoracic clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 50 trials

Recruiting
Not Applicable

Feasibility Study of CBCT for IGRT in Cancer Patients

Breast CancerLiver CancerHead and Neck Cancers+3 more
Varian, a Siemens Healthineers Company50 enrolled4 locationsNCT06681233
Recruiting
Phase 2

HEARTS Trial for Thoracic Cancers

Non-Small Cell Lung Cancer (Stage III)Esophageal Cancer Stage I-IIIEsophagogastric Cancer Stage I-III+2 more
University of Wisconsin, Madison60 enrolled1 locationNCT07132918
Recruiting

Prospective Data Collection Initiative on Thoracic Malignancies

Lung CancerThoracic CancerThymus Cancer+5 more
Dutch Society of Physicians for Pulmonology and Tuberculosis12,000 enrolled10 locationsNCT06996249
Recruiting

Curatively Intended Thoracic Reirradiation

Radiotherapy Side EffectLung CancerThoracic Cancer+2 more
University of Aarhus500 enrolled1 locationNCT06950073
Recruiting
Phase 4

Erector Spinae Block for Thoracic Surgery

Thoracic CancerPulmonary CancerThoracic Neoplasms+2 more
George Washington University70 enrolled1 locationNCT05521789
Recruiting
Phase 1

AMG 193 Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) (MTAPESTRY 104).

Non-small Cell Lung CancerThoracic Tumors
Amgen500 enrolled83 locationsNCT06333951
Recruiting

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

Thoracic CancersLung Cancer NOSMalignant Pleural Mesotheliomas NOS+2 more
National Cancer Institute (NCI)1,310 enrolled1 locationNCT00242723
Recruiting

TBE Zone 2 PMS in Japan

Aneurysm ThoracicDissection of Aorta, ThoracicTrauma
W.L.Gore & Associates200 enrolled1 locationNCT07049913
Recruiting
Phase 2

Study of Tarlatamab as Maintenance Treatment After Chemo-radiotherapy for Limited Stage SCLC Patients

Limited Stage Small Cell Lung CancerThoracic NeoplasmsRespiratory Tract Neoplasms+1 more
Fundación GECP37 enrolled20 locationsNCT07242547
Recruiting
Phase 4

Effects of Ciprofol on Myocardial Injury After Non-cardiac Surgery in Video-Assisted Thoracoscopic Surgery

Thoracoscopic SurgeryThoracic DiseasesMyocardial Injury
Tongji Hospital1,058 enrolled1 locationNCT07028593
Recruiting
Not Applicable

Costotransverse Foramen Block Versus Thoracic Paravertebral Block in Thoracotomy for Lung Cancer

Lung CancerThoracotomyCostotransverse Foramen Block+1 more
National Cancer Institute, Egypt70 enrolled1 locationNCT07367581
Recruiting
Not Applicable

Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine

Quality of LifePain ManagementPulmonary Function+5 more
Lviv National Medical University50 enrolled1 locationNCT07380789
Recruiting

Thoracic Specimen Registry

Lung CancerThoracic DiseasesLung Transplant
Mayo Clinic7,000 enrolled1 locationNCT04118660
Recruiting
Phase 1

Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

Malignant Solid NeoplasmAnatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8+71 more
M.D. Anderson Cancer Center43 enrolled1 locationNCT05092373
Recruiting
Phase 3

Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+10 more
NRG Oncology300 enrolled95 locationsNCT03801876
Recruiting
Phase 2Phase 3

High Dose Dexamethasone to Reduce Postoperative Pain After Video-Assisted Thoracoscopic Surgery Lobectomy /Segmentectomy

Lung Cancer (NSCLC)AnalgeticVideo Assisted Thoracic Surgery (VATS)+1 more
Rigshospitalet, Denmark80 enrolled1 locationNCT07213375
Recruiting
Phase 2

Perioperative Cadonilimab Combined With Neoadjuvant Chemotherapy in Resectable Esophageal Squamous Cell Carcinoma (ESCC)

Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma
Akeso90 enrolled1 locationNCT07263919
Recruiting

Bronchoscopic Lung Ablation of Small Thoracic Tumors: the Blastt Registry

Thoracic Tumors
M.D. Anderson Cancer Center250 enrolled1 locationNCT06840288
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

Lung CancerNSCLCThoracic Cancer+5 more
Tango Therapeutics, Inc.183 enrolled12 locationsNCT06922591
Recruiting
Phase 2

Post-line Treatment With Teniposide for c-Myc-driven Extensive-stage Small Cell Lung Cancer

Lung NeoplasmsThoracic NeoplasmsLung Diseases+1 more
Shanghai Pulmonary Hospital, Shanghai, China15 enrolled1 locationNCT06758700