Thoracic Clinical Trials

180 recruitingLast updated: June 18, 2026

There are 180 actively recruiting thoracic clinical trials across 35 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include Houston, Texas, United States, New York, New York, United States, Philadelphia, Pennsylvania, United States. Updated daily from ClinicalTrials.gov.


Thoracic Trials at a Glance

180 actively recruiting trials for thoracic are listed on ClinicalTrialsFinder across 6 cities in 35 countries. The largest study group is Not Applicable with 83 trials, with the heaviest enrollment activity in Houston, New York, and Philadelphia. Lead sponsors running thoracic studies include M.D. Anderson Cancer Center, Centre Hospitalier Universitaire, Amiens, and Cairo University.

Treatments under study

About Thoracic Clinical Trials

Looking for clinical trials for Thoracic? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Thoracic trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Thoracic clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 180 trials

Recruiting
Not Applicable

Comparison of the Rhomboid Intercostal Block and Serratus Posterior Superior Intercostal Plane Block

Pain, PostoperativeThoracic Surgery, Video-assistedMultimodal Analgesia+2 more
Ankara City Hospital Bilkent90 enrolled1 locationNCT07650877
Recruiting

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

Thoracic CancersLung Cancer NOSMalignant Pleural Mesotheliomas NOS+2 more
National Cancer Institute (NCI)1,559 enrolled1 locationNCT00242723
Recruiting
Not Applicable

A Novel Tobacco Cessation Resource for Smokers With a Diagnosed or Suspected Thoracic Cancer

Cigarette Smoking-Related CarcinomaMalignant Thoracic Neoplasm
Ohio State University Comprehensive Cancer Center30 enrolled1 locationNCT07455513
Recruiting
Phase 1Phase 2

A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors

Thoracic Neoplasms, Lung Diseases, Small Cell Lung Carcinoma
MediLink Therapeutics (Suzhou) Co., Ltd.118 enrolled22 locationsNCT07407933
Recruiting

Bronchoscopic Lung Ablation of Small Thoracic Tumors: the Blastt Registry

Thoracic Tumors
M.D. Anderson Cancer Center250 enrolled1 locationNCT06840288
Recruiting
Not Applicable

Evaluating a Text-Prompt AI Assistant for Chest CT Scans (AI-REPORT Study)

Thoracic Diseases
Shanghai Zhongshan Hospital100 enrolled2 locationsNCT07634861
Recruiting
Not Applicable

Comparison of IV Analgesia Protocols After the Regional Block's Effect Diminishes in Thoracic Surgery

Postoperative PainThoracic Surgery, Video-assistedPatient-controlled Analgesia+2 more
Ankara Etlik City Hospital135 enrolled1 locationNCT07610408
Recruiting

Digital Twin and Ml-basEd MOdel of TEVAR Interventions

Aorta DiseaseAorta, Thoracic Pathologies
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico5,000 enrolled1 locationNCT07640828
Recruiting
Phase 1Phase 2

Ph. I/II Sodium Thiosulfate for OtoProtection During Cisplatin (STOP-CIS)

Head and Neck CancerThoracic CancerTesticular Cancer+1 more
University of Arizona25 enrolled1 locationNCT07407582
Recruiting
Phase 1Phase 2

HEART: Pilot Randomized Controlled Trial

Thoracic Aortic Aneurysm
Mayo Clinic50 enrolled1 locationNCT07483177
Recruiting

A Study of HARMONIC 700 Shears With Advanced Hemostasis in Pediatric and Adult Surgical Procedures

Pediatric Surgical ProceduresAdult Surgical ProceduresAdult Gynecological Procedures+2 more
Ethicon Endo-Surgery165 enrolled9 locationsNCT06608485
Recruiting
Not Applicable

Clinical Study of a New Treatment Model for Elderly Lung Cancer Patients

Lung NeoplasmPerioperative CareAged+2 more
Peking University People's Hospital1,000 enrolled1 locationNCT07632664
Recruiting

Genome Transplant Dynamics

Thoracic Organ Transplantation
National Heart, Lung, and Blood Institute (NHLBI)991 enrolled6 locationsNCT02423070
Recruiting
Phase 1

Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases

Malignant Neoplasm of Bone and Articular CartilageMalignant Neoplasms of Female Genital OrgansMalignant Neoplasms of Independent (Primary) Multiple Sites+7 more
M.D. Anderson Cancer Center44 enrolled1 locationNCT03093909
Recruiting

Incidence of Major Complication in Case of Thoracic Aortic Aneurysm

Thoracic Aortic Aneurysm
University Hospital, Lille320 enrolled1 locationNCT05395598
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

Lung CancerNSCLCThoracic Cancer+5 more
Tango Therapeutics, Inc.183 enrolled18 locationsNCT06922591
Recruiting

Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

Aneurysm ThoracicVascular DiseaseDissection+5 more
W.L.Gore & Associates1,500 enrolled34 locationsNCT06658730
Recruiting
Not Applicable

Parascapular Sub Iliocostalis Plane Block Versus Thoracic Paravertebral Plane Block for Traumatic Multiple Rib Fractures

Discitis of Thoracic Region
Zagazig University36 enrolled1 locationNCT07493473
Recruiting

The Impact of Video-assisted Thoracic Surgery and Regional Anaesthesia on Postoperative Opioid Consumption and Pain Scores

Regional AnaesthesiaThoracic Surgerypostoperative analgesia+2 more
Antalya Training and Research Hospital96 enrolled1 locationNCT07578545
Recruiting
Phase 3

Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+10 more
NRG Oncology300 enrolled95 locationsNCT03801876