Evaluation of an Opioid Stewardship Program in Non-Cancer Patients
Korea University Guro Hospital
70 participants
Jun 27, 2025
INTERVENTIONAL
Conditions
Summary
The objective of this prospective, non-randomized clinical trial is to evaluate the effectiveness of a pharmacist-led Opioid Stewardship Program (OSP) in outpatient adults with chronic non-cancer pain. This study compared OSP implementation with a historical control to determine whether it reduces the incidence of high-risk opioid prescribing and improves patients' awareness, knowledge, and attitudes about opioid use.
Eligibility
Inclusion Criteria3
- Outpatients at the Department of Anesthesiology and Pain Medicine or the Department of Physical Medicine \& Rehabilitation of the study site who received a prescription for opioid analgesics (oral, transdermal, sublingual, or buccal formulations containing oxycodone, fentanyl, tapentadol, hydrocodone, or morphine) due to chronic non-cancer pain during the study evaluation period (from IRB approval date to September 30, 2025)
- Adults aged ≥19 years and <80 years
- Patients who voluntarily signed a written informed consent form after receiving a full explanation of the study and understanding its purpose
Exclusion Criteria9
- Patients with active cancer
- Patients diagnosed with sickle cell disease
- Patients diagnosed with a life-limiting illness eligible for hospice or palliative care as defined in Article 2 of the 'ACT ON HOSPICE AND PALLIATIVE CARE AND DECISIONS ON LIFE-SUSTAINING TREATMENT FOR PATIENTS AT THE END OF LIFE'
- Pregnant patients
- Patients who were prescribed opioid analgesics within the past month for postoperative pain management
- Patients who were prescribed opioid analgesics within the past month for newly developed pain
- Patients with communication difficulties
- Patients who were prescribed buprenorphine for the treatment of opioid use disorder
- Patients who are deemed inappropriate for study participation at the discretion of the investigator
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Interventions
The Opioid Stewardship Program (OSP) includes pain and functional assessments, opioid prescription review and coordination, patient education, and counseling provided by trained pharmacists.
Locations(1)
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NCT07102446