RecruitingNot ApplicableNCT07112287

Germline Testing for Predisposition to Myeloid Malignancies

MyeloGen: Germline Testing for Predisposition to Myeloid Malignancies


Sponsor

Christopher Reilly

Enrollment

200 participants

Start Date

Nov 10, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this research study is to evaluate the feasibility of germline genetic testing using the investigational MyeloGen Gene Panel in adult participants diagnosed with myeloid malignancies.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Age of 18 years or older
  • Participants must have histologically confirmed myeloid malignancy OR bone marrow failure within the last 6 months prior to screening.
  • Ability to understand and provide a signed and completed consent document in English.

Exclusion Criteria2

  • Participants who cannot safely undergo clinically indicated skin biopsy as adjudicated by the study team.
  • Participants who have previously undergone germline genetic testing for predisposition to myeloid malignancies

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Interventions

DEVICEMyeloGen Gene Panel

The MyeloGen Gene Panel is investigational Germline genetic testing using skin fibroblasts.


Locations(1)

Dana-Farber Cancer Institute

Boston, Massachusetts, United States

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NCT07112287


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