RecruitingNot ApplicableNCT07116161

Exercise Therapy and Cognitive Behavioural Therapy for Fatigue in Female Cancer Patients in Singapore

Pilot Study of Exercise Therapy and Cognitive Behavioural Therapy for Fatigue in Female Cancer Patients in Singapore

Sponsor

National Cancer Centre, Singapore

Enrollment

100 participants

Start Date

Jul 14, 2025

Study Type

INTERVENTIONAL

Conditions

Breast Cancer Female Fatigue

Summary

The purpose of this research study is to investigate the acceptability, feasibility, and effectiveness of exercise therapy and cognitive behavioral therapy (CBT) in improving fatigue levels and breast cancer treatment adherence in breast cancer patients.

Eligibility

Sex: FEMALEMin Age: 21 Years

Plain Language Summary

Simplified for easier understanding

This trial tests a combined program of supervised exercise therapy and cognitive behavioral therapy (CBT) to reduce cancer-related fatigue in female breast cancer patients in Singapore who have completed their primary cancer treatment. **You may be eligible if...** - You are a woman 21 or older - You have been diagnosed with Stage I–III breast cancer - You have completed surgery and, if required, chemotherapy - You are experiencing significant fatigue (score 4 or more on a fatigue scale) - You can communicate in English or Mandarin **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have dementia or a major psychiatric condition - Your medical team considers you unfit for light-to-moderate exercise - You have uncontrolled pain or very low blood counts - You have serious heart problems (e.g., heart failure or severe arrhythmia) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERGraded Exercise Therapy Arm (GET)

Consists of a self-supervised individualized exercise prescription by the rehabilitation professional consisting of aerobic (e.g. brisk walking / cycling) and resistance training exercises, customized by patient preference.

OTHERExperimental: Exercise Therapy (GET) plus Cognitive Behavioural Therapy (CBT)

Consists of four major components adapted from previous studies,13,15,16 and delivered by qualified and trained study psychologists. First, the ABCD model of cognitive behavioural therapy (A: activating events, B: beliefs, C: consequences, D: Dispute) will be taught and applied to identify negative, unhelpful beliefs and the emotional, behavioural and physical consequences of those beliefs. Second, patients were taught behavioural strategies to manage fatigue (e.g. sleep hygiene, activity scheduling). Lastly, participants will be guided to reformulate dysfunctional cognitions regarding fatigue, improve coping strategies in relation to significant others (e.g. family, friends) and set goals.