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RecruitingPhase 2NCT07118618

Probenecid Administration for Alcohol Craving and Consumption

Probenecid, Pannexin 1 Channels for Alcohol Use Disorder

Sponsor

Brown University

Enrollment

120 participants

Start Date

Mar 14, 2026

Study Type

INTERVENTIONAL

Conditions

Alcohol ConsumptionAlcohol Use Disorder (AUD)Craving

Summary

This study proposes a 16-week, between-subject, double-blind, randomized controlled trial (RCT) with probenecid (2g /day) compared to placebo in individuals with AUD to test if reduces craving and alcohol consumption.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo Oral Tablet and a drug called Probenecid Oral Tablet for people with alcohol consumption, alcohol use disorder (aud), and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGProbenecid Oral Tablet

2gr daily

DRUGPlacebo Oral Tablet

Inactive compound

Locations(1)

Brown University

Providence, Rhode Island, United States

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NCT07118618

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