Efficacy & Safety of Anticoagulants in Cirrhosis ± HCC

This study is looking at the safety and effectiveness of blood thinners (anticoagulants) in people with cirrhosis (scarring of the liver) who have developed a blood clot in the portal vein — a major vein that supplies the liver. Some participants also have liver cancer (HCC). **You may be eligible if...** - You have liver cirrhosis (confirmed scarring of the liver) - You have a clot in the portal vein - Your liver disease is classified as Child-Pugh A or B (moderate severity) - You may or may not have hepatocellular carcinoma (HCC, a type of liver cancer) **You may NOT be eligible if...** - Your platelet count is very low (below 10,000) - Your creatinine (kidney function marker) is above 1.9 - You have Budd-Chiari syndrome (a different type of liver blood clot condition) - You have active, uncontrolled bleeding Talk to your doctor to see if this trial is right for you.