RecruitingNot ApplicableNCT07176494

Revision of Deep Brain Stimulator in Patients With Parkinson's Disease

Revision of Deep Brain Stimulator in Patients With Parkinson's Disease: A Comparison of Perioperative Characteristics of Regional and General Anesthesia


Sponsor

Ankara Etlik City Hospital

Enrollment

50 participants

Start Date

Sep 20, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Parkinson's disease is a chronic and progressive neurodegenerative disease that affects the central nervous system, particularly impairing movement control. It is associated with the loss of dopamine-producing cells in the brain and typically occurs in middle age and beyond. Deep brain stimulation (DBS) is considered when symptoms of Parkinson's disease, such as tremors, slowed movements, and muscle rigidity, are not adequately controlled with medications. Selected patients with severe symptoms that do not respond to medical treatment are generally considered for this treatment. Battery revision surgeries can be performed under general anesthesia or regional anesthesia. Patients undergoing general anesthesia should be cautious about the potential complications of general anesthesia, while those undergoing regional anesthesia should be cautious about the local anesthetic systemic toxicity. Because each method has its own advantages, the choice of anesthesia may vary. This study aimed to compare postoperative analgesic efficacy and patient satisfaction in patients who underwent surgery under general anesthesia or sedation-assisted battery replacement under regional anesthesia. Both anesthesia methods are routinely used in Parkinson's disease patients undergoing battery replacement.


Eligibility

Min Age: 40 YearsMax Age: 85 Years

Inclusion Criteria3

  • Those aged 40-85
  • Those with an ASA score of I-II-III
  • Those with a body mass index (BMI) between 18-30

Exclusion Criteria3

  • Those under 40 and over 85
  • Those with an ASA score of IV or higher
  • Those with a BMI of under 18 and over 30

Interventions

PROCEDUREPatients who underwent surgery under general anesthesia

Patients undergoing surgery under general anesthesia will undergo general anesthesia induction. During the skin closure, patients received 50 mg of dexketoprofen. Additionally, a paracetamol dose of 1 g every 8 hours and a dexketoprofen dose of 50 mg twice daily were administered intravenously for multimodal analgesia.

PROCEDUREPatients who underwent surgery under regional anesthesia

25 cc (15 cc 0.5% bupivacaine + 5 cc 2% lidocaine + 5 cc isotonic) local anesthetic solution is prepared. 10 cc of the medication is administered into the interpectoral plane, and 15 cc into the pectoserratus plane. During the skin closure, patients received 50 mg of dexketoprofen. Additionally, a paracetamol dose of 1 g every 8 hours and a dexketoprofen dose of 50 mg twice daily were administered intravenously for multimodal analgesia.


Locations(1)

Ankara Etlik City Hospital

Ankara, Yenimahalle\Ankara, Turkey (Türkiye)

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NCT07176494


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